Dental Caries is a multifactorial disease. Four major factors directly contribute the dental caries, host, cariogenic biofilm, fermentable carbohydrate and time. The four factors must be present, without any one of these, there is not to be dental caries. Specific important pathogens in the oral biofilm include mutans streptococci (MS
Oleh :
Dhyani Widhianingsih